The age of the female is an important factor for In Vitro Fertilization (IVF). By applying Preimplantation Genetic Diagnosis (PGD) to the patient who is over the age of 40, and is considered to have good ovarian capacity, it is possible to achieve pregnancy by 25-30%.
If hormone tests that are performed on the 3rd day of menstruation and the ultrasonography showing that ovarian capacity and functions are appropriate, it is possible to apply IVF until the age of 45. However, it is recommended to investigate whether embryos are normal in terms of chromosomes with the Preimplantation Genetic Diagnosis (PGD) method.
Nowadays, in spite of the wide range of treatment that is available for all types of male infertility, the biggest obstacle for the treatment is the age of the female. The ovarian reserve of a new born girl, which is between one to two million at that time, decreases to 250-300 thousand within the first menstrual period, and keeps decreasing until menopause. Advancing age decreases the reserve especially after the age of 37, and the loss rate in the ovarian reserve is evident.
Additionally, the quality of the eggs deteriorate with advancing age, which reduces the chance of getting pregnant and having a healthy child. Therefore, miscarriages in the early stages of pregnancy are more common than the younger aged women. The age of females and the low ovarian reserve as a result of aging are the most important factors that affect fertility success. A 25-30% success in pregnancy is acquired with women who are over 40 and are seen to have good ovarian capacity, all through the application of the Preimplantation Genetic Diagnosis (PGD).
PGD can be applied in order to increase the chances of continuing pregnancy and having a healthy child. With this technique, the chromosomes, which are observed to be more problematic at that age, are investigated before transferring to the uterus, so that the transfer of abnormal embryos is avoided. Loss in the ovarian reserve may sometimes occur at younger ages, and the ovarian reserve of older women may be higher than expected. Thus, it is very significant to identify the ovarian reserve of women with extensive examination, ultrasonography, and hormone tests and be able to reveal the chances of success for patients.
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