Gender Selection / Family Balancing (PGD)

Gender Selection: PGD (preimplantation genetic diagnosis) ~100% Accuracy~

This technology enables our expert staff to genetically evaluate the embryos before we transfer them into the womb. As the first step of gender selection, the embryos should be on Day 3 embryos which display 4 to 10 cells and a single nucleus so that we can apply PGD. Removing one or two cells from embryos with suitable morphology with the aid of a biopsy pi

a Girl or a Boy?

pette is the first step. Afterwards, the appropriate genetic examination starts. You may wonder whether this procedure is harmful to the embryo. Actually, according to the experts, it does not compromise subsequent embryo development as long as we perform the procedure properly and gently. Depending on the result of PGD, transferring embryos with normal genetic content to the patient is the last step.

We apply ~Gender Selection: PGD~ under these circumstances;

after a minimum of two to three failed attempts
recurrent miscarriages
hereditary disease in the family history
advanced maternal age (You can also check our article “Age Factor“
sex chromosomes transmitting diseases
HLA (human leukocyte antigen) typing
Sex selection (family balancing)

Gender Selection: PGD PROCEDURE:

The first step is the biopsy procedure. An experienced embryologist performs it in the laboratory. He or she takes the biopsy from the polar body of the egg before and/or after fertilization or from the cells of the embryo. The latter is more extensively used. Subsequently, he or she removes one or two cells from the embryos with the aid of a pipette.
The second step is the fixation procedure. He or she fix the cells removed from the embryos onto glass slides. The exposion of their genetic content is the next step. Later on, the genetic laboratory evaluates the results.

At the last step, the genetic laboratory examines the material. In that manner, there are two basic examination techniques;

First, the FISH (fluorescent in situ hybridization) technique:

In this technique, the fixed cells are stained with special probes which detect the abnormality. Then, examination of those takes place in the laboratory. As these probes are attached to fluorescent substances, they transmit signals under ultraviolet light. Nowadays probes with various colors for every examined chromosome are available. In fact, it is possible to examine two to three regions of the same preparation. The number of diseases and the possibility of their diagnosis are increasing day by day.
Second, PCR (polymerase chain reaction) technique:

We use it for detecting single gene disorders. It is possible that PGD could improve pregnancy rates because it selects embryos that are genetically normal for transfer. However, PGD, is not a therapeutical approach but is a diagnostic tool.

If you would like to learn more about this procedure, please contact us via form orWhatsapp!